The Orange Peel http://theorangepeel.net
Jack of the Wood http://www.jackofthewood.com/ The Grey Eagle http://www.thegreyeagle.com
The Magnetic Field http://www.themagnetictheatre.org Tressa’s http://www.tressas.com

Another good resource is the Asheville music link:

http://www.ashevillenc.com/events/music